ALBUMIN MACRO-AGGREGATE (MAA)

Following injection into a superficial vein of the venous circulatory system, the macroaggregates are transported to the
The particles of the albumin macroaggregate do not penetrate into the pulmonary parenchyma (interstitial or alveolar) but remain in an interstitial or alveolar layer. The particles of the albumin macroaggregate do not penetrate into the lung parenchyma (interstitial or alveolar) but are held in a
temporary occlusive position in the lumen of the capillaries. When the pulmonary distribution flow is normal, the compound is distributed throughout the pulmonary area, following physiological gradients, when the flow is altered, a proportionally smaller amount of particles reaches the areas of reduced flow. The cause of the decrease in pulmonary concentration is the mechanical rupture of the particles clogging the capillaries, due to the systodiastolic pressure of the pulsations inside the capillaries themselves. The microcolloids are metabolized, introducing radioactive labeling (^99mTc) into the systemic circulation, from which they are eliminated and excreted through urine. Diagnostic indications: it is used for lung perfusion scintigraphy, and as a secondary indication it can be used in venogammagraphy.

Category: TECHNETIUM TRACERS

Sub - Category: DIAGNOSIS